Acute digital ischemia: A rare presentation of antisynthetase syndrome

Acute digital ischemia: A rare presentation of antisynthetase syndrome.

Antisynthetase syndrome (ASS) is recognized as a subgroup of idiopathic inflammatory myopathies (IIMs). It is associated with autoantibodies directed against aminoacyl-transfer ribonucleic acid (tRNA) synthetase enzymes. We report the first case of anti-PL-7/anti-SSA 52kD ASS presenting as acute digital ischemia, an association not described previously. Occlusive vasculopathy is a rare but seri...

Sheehan’s syndrome presenting as psychosis: a rare clinical presentation

 Sheehan’s syndrome (SS) refers to the occurrence of varying degree of hypopituitarism after parturition (1). It is a rare cause of hypopituitarism in developed countries owing to advances in obstetric care and its frequency is decreasing worldwide. However, it is still frequent in underdeveloped and developing countries. Sheehan’s syndrome is often diagnosed late as it evolves slowly (2,3). Re...

acute abdomen : a rare presentation of chickenpox

conclusions atypical chickenpox infections should be suspected in any patient who presents unexplained abdominal pain, fever, and dyspnea, even if cutaneous lesions are minimal. an early diagnosis can prevent a fatal outcome. introduction infection with varicella-zoster virus (vzv) in healthy adults tends to be more severe. antiviral medication (often prescribed for adults), is effective in red...

Acute respiratory distress syndrome: A rare presentation of amantadine toxicity

PATIENT Male, 64 FINAL DIAGNOSIS: Acute Respiratory Distress Syndrome (ARDS) Symptoms: Generalized myoclonic jerks • impaired concentration • memory decline • visual hallucinations MEDICATION Amantadine HCl Clinical Procedure: - Specialty: Toxicology. OBJECTIVE Adverse events of drug therapy. BACKGROUND Amantadine is indicated for treatment of influenza A infection, Parkinson disease and ...

Antisynthetase syndrome